Soft tissue
Fibroblastic / myofibroblastic tumors
Superficial acral fibromyxoma

Author: Lauren N. Stuart, M.D., M.B.A. (see Authors page)
Editor: Jerad M. Gardner, M.D.

Revised: 12 September 2016, last major update April 2013

Copyright: (c) 2002-2016, PathologyOutlines.com, Inc.

PubMed Search: Superficial acral fibromyxoma

Cite this page: Superficial acral fibromyxoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/softtissuesuperficialacral.html. Accessed December 8th, 2016.
Definition / General
  • Name is accurate - superficial tumor of fingers and toes with bland fibromyxoid histology
  • First described in 2001 (Hum Pathol 2001;32:704)
Terminology
Epidemiology
Sites
Clinical Features
Prognostic Factors
  • Local recurrence almost always associated with positive margins
Case Reports
Treatment
Gross Description
  • Well circumscribed, non encapsulated gray-white nodule
  • Can be dome shaped, polypoid, verrucous
  • Cut surface firm, gelatinous, solid (Arch Pathol Lab Med 2011;135:1064)
Micro Description
  • Dermal or subcutaneous tumor composed of bland spindle and stellate cells within a myxoid or collagenous stroma with prominent vessels and mast cells
  • Cells are arranged in random, loose storiform and fascicular growth patterns
  • Mild nuclear atypia
  • Occasional multinuclear stromal cells
  • Rare mitotic figures
Micro Images

Images hosted on other servers:

Tumor at tip of big toe

Spindle cells and mast cells in myxoid matrix

CD34+

CD99+

Spindle cell proliferation

H&E, CD10 and nestin

Positive Stains
Differential Diagnosis