Soft tissue
Benign vascular lesions
Hereditary hemorrhagic telangiectasia

Author: Vijay Shankar, M.D.

Revised: 31 January 2018, last major update November 2012

Copyright: (c) 2002-2018,, Inc.

PubMed search: Hereditary hemorrhagic telangiectasia [title]

Related topics: Vascular ectasias

Page views in 2018: 513
Page views in 2019 to date: 283
Cite this page: Shankar, V. Hereditary hemorrhagic telangiectasia. website. Accessed June 25th, 2019.
Definition / general
  • Also known as Osler-Rendu-Weber syndrome
  • Autosomal dominant disorder in which localized capillary dilation causes arterial blood to be shunted directly into postcapillary venules from birth
  • Dilated capillaries and veins are present over skin and mucous membranes of GI, GU, lips, oral cavity, respiratory
  • May bleed into gut, nose, urine (Am Fam Physician 2010;82:785)
  • Patients have mutations in two transforming growth factor-beta binding proteins including endoglin
Case reports
Clinical images
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Fingertips, tongue, stomach

Nasal mucosa


Microscopic (histologic) images
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Dilated capillaries lined by flat endothelial cells

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