Spleen
Infectious / inflammatory disorders
AIDS

Author: Jaleh Mansouri, M.D. (see Authors page)

Revised: 1 March 2018, last major update October 2012

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Spleen[TI] AIDS[TIAB]

Table of Contents
Definition / general
Cite this page: Mansouri, J. AIDS. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/spleenAIDS.html. Accessed July 16th, 2018.
Definition / general
  • Prior to highly active antiretroviral therapy (HAART), typical findings were white pulp depletion, hemosiderin deposition, spindle cell proliferation and perivascular hyalinization; also infectious and malignant infiltrates (Mod Pathol 2002;15:406)
  • Post-HAART findings include less frequent white pulp depletion but similar rates of splenic involvement by atypical mycobacteria and CMV in those with systemic disease