Table of ContentsDefinition / general
Cite this page: Mansouri, J. AIDS. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/spleenAIDS.html. Accessed March 22nd, 2018.
Definition / general
- Prior to highly active antiretroviral therapy (HAART), typical findings were white pulp depletion, hemosiderin deposition, spindle cell proliferation and perivascular hyalinization; also infectious and malignant infiltrates (Mod Pathol 2002;15:406)
- Post-HAART findings include less frequent white pulp depletion but similar rates of splenic involvement by atypical mycobacteria and CMV in those with systemic disease