Lymph nodes & spleen, nonlymphoid
Spleen-infectious / inflammatory disorders
Splendore-Hoeppli phenomenon

Topic Completed: 1 October 2012

Minor changes: 4 July 2020

Copyright: 2003-2019,, Inc.

PubMed Search: Splendore-Hoeppli phenomenon[TI]

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Cite this page: Mansouri J. Splendore-Hoeppli phenomenon. website. Accessed July 8th, 2020.
Definition / general
  • Abscess containing brightly eosinophilic, pseudomycotic structures composed of necrotic debris and immunoglobulin in starburst pattern
  • In U.S., usually due to Staphylococcus aureus or Pseudomonas aeruginosa; in tropics, due to schistosomiasis, microfilariae, various fungi
Case reports
Microscopic (histologic) images

Images hosted on other servers:

A / B: abscesses with brightly eosinophilic crystalline structures in starburst pattern; C: gram stain and D: modified acid fast stain show gram positive, partially acid fast filamentous organisms, consistent with Nocardia

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