Infectious / inflammatory disorders
Acute splenitis

Author: Jaleh Mansouri, M.D. (see Authors page)

Revised: 1 March 2018, last major update October 2012

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Acute splenitis

Cite this page: Mansouri, J. Acute splenitis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/spleenacutesepticsplenitis.html. Accessed March 24th, 2018.
Definition / general
  • Also called acute splenic tumor or septic spleen
  • Although traditionally associated with bacteremia, only known study shows no correlation (Arch Pathol Lab Med 2001;125:888)
Gross description
  • Splenic parenchyma may "flow" from cut surface
Microscopic (histologic) description
  • Criteria are ill defined but traditionally are acute congestion of red pulp with numerous neutrophils in red and white pulp
  • Necrosis of follicles occurs with group A streptococcal infection
  • No capsular invasion by immunoblasts
Microscopic (histologic) images

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Various images

Differential diagnosis