Cite this page: Mansouri, J. Asplenia (congenital absence of spleen). PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/spleenasplenia.html. Accessed March 22nd, 2018.
Definition / general
- Rare, associated with cardiac malformations (80%, usually involving atrioventricular endocardial cushion and ventricular outflow tract), situs inversus, anomalies of blood vessels, lung, abdominal viscera
- Can present with pneumococcal sepsis (OPSI)
- Familial congenital asplenia (Eur J Pediatr 2010;169:315)