Cite this page: Mansouri J. Castleman disease. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/spleencastleman.html. Accessed October 21st, 2019.
Definition / general
- Also called angiofollicular lymph node hyperplasia
- Usually no prominent splenomegaly
Microscopic (histologic) description
- Usually plasma cell type with white pulp hyperplasia and prominent plasmacytosis (Am J Surg Pathol 1988;12:176)
- Also hyaline vascular type with white pulp hyperplasia and numerous atrophic and hyaline vascular germinal centers, only rare plasma cells