Lymph nodes & spleen, nonlymphoma
Spleen-infectious / inflammatory disorders

Topic Completed: 1 October 2012

Minor changes: 4 July 2020

Copyright: 2003-2019,, Inc.

PubMed Search: Hantavirus spleen

Page views in 2019: 50
Page views in 2020 to date: 82
Cite this page: Mansouri J. Hantavirus. website. Accessed November 30th, 2020.
Definition / general
  • Rare but deadly disease transmitted to humans through aerosolized virus from rodent urine, droppings or saliva
  • Usually causes pulmonary syndrome with acute respiratory distress syndrome
Gross description
  • Dense, rubbery and heavy lungs floating within yellow serous fluid within pleural cavity
  • No specific splenic findings
Microscopic (histologic) description
  • Spleen: generalized capillary dilation and edema, immunoblasts in red pulp and periarteriolar sheaths of spleen, occasional prominent and swollen endothelial cells
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