Infectious / inflammatory disorders

Topic Completed: 1 October 2012

Minor changes: 18 March 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed Search: Hantavirus spleen

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Cite this page: Mansouri J. Hantavirus. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/spleenhantavirus.html. Accessed May 30th, 2020.
Definition / general
  • Rare but deadly disease transmitted to humans through aerosolized virus from rodent urine, droppings or saliva
  • Usually causes pulmonary syndrome with acute respiratory distress syndrome
Gross description
  • Dense, rubbery and heavy lungs floating within yellow serous fluid within pleural cavity
  • No specific splenic findings
Microscopic (histologic) description
  • Spleen: generalized capillary dilation and edema, immunoblasts in red pulp and periarteriolar sheaths of spleen, occasional prominent and swollen endothelial cells
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