Infectious / inflammatory disorders

Author: Jaleh Mansouri, M.D. (see Authors page)

Revised: 1 March 2018, last major update October 2012

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Hantavirus spleen

Cite this page: Mansouri, J. Hantavirus. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/spleenhantavirus.html. Accessed August 20th, 2018.
Definition / general
  • Rare but deadly disease transmitted to humans through aerosolized virus from rodent urine, droppings or saliva
  • Usually causes pulmonary syndrome with acute respiratory distress syndrome
Gross description
  • Dense, rubbery and heavy lungs floating within yellow serous fluid within pleural cavity
  • No specific splenic findings
Microscopic (histologic) description
  • Spleen: generalized capillary dilation and edema, immunoblasts in red pulp and periarteriolar sheaths of spleen, occasional prominent and swollen endothelial cells