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Spleen
Hematogenous neoplasms
Hairy cell leukemia

Reviewer: Jaleh Mansouri, M.D. (see Reviewers page)
Revised: 13 April 2013, last major update January 2013
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.

See variant type below

General
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Case reports
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Treatment
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Gross description
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Micro description
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Spleen: Bone marrow:
Micro images
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Figure 1
TIA1+
Bone marrow smear

Fig 1: Large lymphocytes with abundant cytoplasm, eccentric nuclei, often cytoplasmic projections; 2: TRAP+; 3: hypercellular bone marrow with "fried egg" lymphocytes that are monotonous with abundant cytoplasm

Bone marrow aspirate
CD11c+
CD20+
CD25+
DBA44+


Positive stains
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Negative stains
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Electron microscopy description
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Molecular / cytogenetics description
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Molecular / cytogenetics images
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BRAF V600E Mutation in Hairy-Cell Leukemia (HCL), as Compared with Other Peripheral B-Cell Neoplasms


Differential diagnosis
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Additional references
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Variant type
General
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Case reports
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Micro description
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Micro images
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Various images


Flow cytometry images
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Various images


Positive stains
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Negative stains
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Differential diagnosis
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Additional references
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End of Spleen > Hematogenous neoplasms > Hairy cell leukemia


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