Spleen
Vascular tumors
Hemangiopericytoma

Author: Vijay Shankar, M.D. (see Authors page)

Revised: 8 March 2018, last major update December 2013

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Hemangiopericytoma spleen

Cite this page: Shankar, V. Hemangiopericytoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/spleenhpc.html. Accessed July 16th, 2018.
Definition / general
  • Very rare vascular neoplasm of uncertain biological behavior
Epidemiology
  • Primarily affects middle aged adults
  • Males and females are equally affected
Clinical features
  • Usually asymptomatic, can present with splenomegaly
  • Can present with hemoperitoneum due to spontaneous or traumatic rupture
Diagnosis
  • CT or MRI, then histopathological confirmation
Radiology images

Images hosted on other servers:

Active bleeding in splenic cystic lesion

Case reports
Treatment
  • Partial or total splenectomy
Gross description
  • Single or multiple, encapsulated, soft to rubbery
  • Average size is 6.5 cm
Gross images

Images hosted on other servers:

Lobulated, solid, well circumscribed nodules

Microscopic (histologic) description
  • Well developed, branching, thick walled blood vessels surrounded by connective tissue sheath
  • Monotonous cells with moderate to high cellularity
  • Hemorrhagic and cystic degeneration can be seen
  • Rarely manifest as multiple abscesses
Microscopic (histologic) images

Images hosted on other servers:

Dilated sinuous vascular channels (H&E and reticulin)

Positive stains
Molecular / cytogenetics description