Spleen
Infectious / inflammatory disorders
Malaria

Author: Jaleh Mansouri, M.D. (see Authors page)

Revised: 1 March 2018, last major update October 2012

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Malaria[TI] spleen[TI]

Cite this page: Mansouri, J. Malaria. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/spleenmalaria.html. Accessed July 16th, 2018.
Definition / general
  • May result in splenic rupture, infarction or rarely sudden death, especially with infection by Plasmodium falciparum (Leg Med (Tokyo) 2012;14:111)
Case reports
Microscopic (histologic) description
  • Hallmark finding is vascular congestion with adherence to endothelial wall by parasitized red blood cells, macrophages contain brown malarial pigment, disorganized architecture with loss of marginal zone and ill defined T cell zones (Cell Microbiol 2012;14:343)