Spleen
Other tumors
Metastases


Topic Completed: 1 February 2014

Revised: 19 March 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed Search: Metastases[TI] spleen[TI]

Vijay Shankar, M.D.
Page views in 2018: 497
Page views in 2019 to date: 399
Cite this page: Shankar V. Metastases. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/spleenmetastases.html. Accessed November 13th, 2019.
Definition / general
  • Splenic metastasis is usually associated with extensive metastases - isolated splenic metastasis is rare
Sites
Pathophysiology
  • Metastasis may be rare due to spleen's immunological function
  • Metastases developed by hematogenous, lymphatic or abdominal cavity implantation routes; also direct invasion from lesions in adjacent organs
  • Hematogenous or direct seeding is more common
Clinical features
  • No specific clinical presentation
  • Rarely present with splenic rupture
Diagnosis
  • By radiological examination followed by histopathological confirmation
Radiology description
  • In ultrasonographic examination, the metastatic foci in the spleen may be hyperechoic, hypoechoic or nonechoic
  • In CT, hypodense lesions are seen
Radiology images

Images hosted on other servers:

F-FDG PET images of splenic metastasis

CT images of splenic metastasis

Case reports
Treatment
  • Splenectomy and chemotherapy depending on the primary tumor
Gross description
  • Splenic metastasis can be seen as solitary nodule, multiple nodules or diffuse infiltration or cyst
  • Rarely resembles follicular lymphoma grossly with multiple nodules
Microscopic (histologic) description
Microscopic (histologic) images

Images hosted on other servers:

Parotid gland: carcinoma ex pleomorphic adenoma

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