Lymph nodes & spleen, nonlymphoma

Topic Completed: 1 October 2012

Minor changes: 22 July 2020

Copyright: 2003-2020,, Inc.

PubMed Search: Parvovirus[TI] spleen

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Cite this page: Mansouri J. Parvovirus. website. Accessed November 30th, 2020.
Definition / general
  • Causes "fifth" disease in children, a mild illness with a "slapped cheek" facial rash
  • Pregnant women may pass virus to fetus, where it causes marked fetal anemia and hydrops
  • Attacks erythroblasts, affecting those with minimal reserve (sickle cell patients, fetuses)
Microscopic (histologic) images

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Erythroid precursors with large pink inclusions

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