Spleen
Other nonneoplastic disorders
Peliosis

Author: Jaleh Mansouri, M.D. (see Authors page)

Revised: 2 March 2018, last major update October 2012

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Peliosis[TI] spleen

Cite this page: Mansouri, J. Peliosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/spleenpeliosis.html. Accessed August 20th, 2018.
Definition / general
  • Also called peliosis lienis
  • Multiple blood filled cystic spaces
  • Usually associated with peliosis hepatis but may be independent
  • Multiple pathogenetic mechanisms possible - may be caused by infection with Bartonella henselae in HIV patients with bacillary angiomatosis
  • May cause splenic rupture and death, particularly in patients with carcinomatosis, chronic leukemia, post liver transplantation, recipients of anabolic androgenic steroids, tuberculosis
Case reports
Microscopic (histologic) description
  • Blood filled sinuses with reduced lining cells, similar to hairy cell leukemia
Microscopic (histologic) images

Images hosted on other servers:

Splenic peliosis

Differential diagnosis
Additional references