Table of Contents
Definition / general | Case reports | Microscopic (histologic) description | Microscopic (histologic) images | Differential diagnosis | Additional referencesCite this page: Mansouri J. Peliosis. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/spleenpeliosis.html. Accessed April 19th, 2024.
Definition / general
- Also called peliosis lienis
- Multiple blood filled cystic spaces
- Usually associated with peliosis hepatis but may be independent
- Multiple pathogenetic mechanisms possible - may be caused by infection with Bartonella henselae in HIV patients with bacillary angiomatosis
- May cause splenic rupture and death, particularly in patients with carcinomatosis, chronic leukemia, post liver transplantation, recipients of anabolic androgenic steroids, tuberculosis
Case reports
- 56 year old woman with abdominal pain and anorexia (Br J Radiol 2010;83:e126)
- 62 year old man with peliosis and splenic rupture secondary to untreated chronic myelomonocytic leukemia (Am J Surg Pathol 1983;7:197)
Microscopic (histologic) description
- Blood filled sinuses with reduced lining cells, similar to hairy cell leukemia
Microscopic (histologic) images
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Splenic peliosis
Differential diagnosis
Additional references
