Author: Jaleh Mansouri, M.D. (see Authors page)

Revised: 28 February 2018, last major update October 2012

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Spleen rupture[TI]

Cite this page: Mansouri, J. Rupture. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/spleenrupture.html. Accessed July 17th, 2018.
Definition / general
  • Due to blunt trauma or abdominal surgery, causing hemoperitoneum and emergency splenectomy
  • Only rarely ruptures spontaneously (associated with acute splenitis, amyloidosis [rare], infectious mononucleosis, inflammatory disorders, leukemia / lymphoma, malaria, other tumors, peliosis lienis, pregnancy, subacute bacterial endocarditis, typhoid fever)
  • Splenic rupture may be delayed after trivial / minor trauma
Case reports
Clinical images

Images hosted on other servers:

Grossly enlarged with hematoma

Gross description
  • Rupture may be a very small capsular tear, often in superior pole or hilum
Microscopic (histologic) description
  • Neutrophils below capsular tear with intraparenchymal hemorrhage; also lymphoid hyperplasia with prominent marginal zone
Microscopic (histologic) images

Images hosted on other servers:

Subcapsular splenic nodule in splenic pregnancy

Due to pancreatic adenocarcinoma

Additional references