Topic Completed: 1 October 2012

Revised: 15 March 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed Search: Spleen rupture[TI]

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Cite this page: Mansouri J. Rupture. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/spleenrupture.html. Accessed October 21st, 2019.
Definition / general
  • Due to blunt trauma or abdominal surgery, causing hemoperitoneum and emergency splenectomy
  • Only rarely ruptures spontaneously (associated with acute splenitis, amyloidosis [rare], infectious mononucleosis, inflammatory disorders, leukemia / lymphoma, malaria, other tumors, peliosis lienis, pregnancy, subacute bacterial endocarditis, typhoid fever)
  • Splenic rupture may be delayed after trivial / minor trauma
Case reports
Clinical images

Images hosted on other servers:

Grossly enlarged with hematoma

Gross description
  • Rupture may be a very small capsular tear, often in superior pole or hilum
Microscopic (histologic) description
  • Neutrophils below capsular tear with intraparenchymal hemorrhage; also lymphoid hyperplasia with prominent marginal zone
Microscopic (histologic) images

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Subcapsular splenic nodule in splenic pregnancy

Due to pancreatic adenocarcinoma

Additional references
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