Cite this page: Mansouri, J. Wegener granulomatosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/spleenwegenersgranulomatosis.html. Accessed July 23rd, 2018.
Definition / general
- Splenic involvement rarely diagnosed during life but occurs more frequently than clinically evident (Arch Pathol Lab Med 1996;120:974)
Microscopic (histologic) description
- Necrotizing granulomatous inflammation, vasculitis with fibrinoid necrosis, vascular thrombosis, diffuse hyalinization of blood vessels, infarction, microcalcifications, hemosiderin deposition