Author: Nat Pernick, M.D. (see Authors page)

Revised: 3 September 2015, last major update July 2013

Copyright: (c) 2003-2015,, Inc.

PubMed Search: 15-PGDH

PGE2 synthesis, degradation and regulation

Uses by Pathologists
  • Apocrine marker for benign and most malignant apocrine breast lesions
Micro Images

Bladder: normal (left) and carcinoma

Breast: benign apocrine and malignant lesions

Colon: normal

Colon: normal and cancer

Liver: normal

Lung: normal and carcinoma

Prostate: normal

Stomach: normal and cancer

Synovium: healthy and inflamed

Synovium: rheumatoid arthritis

Uterus: endometrial adenocarcinoma

Positive Staining - Normal
  • Apocrine sweat glands; various epithelium
Positive Staining - Disease