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Stains
BG7
Authors: Kara Hamilton, M.S., Nat Pernick, M.D., PathologyOutlines.com, Inc.
Revised: 12 April 2012, last major update March 2010
Copyright: (c) 2010-2012, PathologyOutlines.com, Inc.
Terminology
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● Also called BG-7, anti-Lex, Lewis X antibody
Physiology
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● Recognizes the type 2 chain of the Lewis X blood group antigen
Uses
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● Possibly for screening high risk population for bladder carcinoma (J Urol 2002;168:470)
Positive stains - normal
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● Granulocytes
● Some endothelial cells or erythrocytes
Positive stains - disease
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● Bladder carcinoma
● Reed-Sternberg cells (Cancer 1991;67:1338)
● Granulocytic sarcoma
● Rare epithelioid histiocytes
Negative stains
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● Interdigitating reticulum cell sarcoma
● Langerhans cell histiocytoma
● Malignant histiocytosis
● Monoblastic leukemia
● Reticulohistiocytoma
● Most reactive lymph node conditions
End of Stains > BG7
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