Author: Kara Hamilton, M.S., Nat Pernick, M.D. (see Authors page)

Revised: 29 October 2015, last major update July 2013

Copyright: (c)2003-2015,, Inc.

PubMed Search: BG7
Definition / General
  • Also called BG-7, anti-Lex, Lewis X antibody
  • Physiology: recognizes the type 2 chain of the Lewis X blood group antigen
Uses by Pathologists
Positive Staining - Normal
  • Granulocytes
  • Some endothelial cells or erythrocytes
Positive Staining - Disease
  • Bladder carcinoma
  • Reed-Sternberg cells (Cancer 1991;67:1338)
  • Granulocytic sarcoma
  • Rare epithelioid histiocytes
Negative Staining
  • Interdigitating reticulum cell sarcoma
  • Langerhans cell histiocytoma
  • Malignant histiocytosis
  • Monoblastic leukemia
  • Reticulohistiocytoma
  • Most reactive lymph node conditions