Pathology Outlines

Stains
BG7

Author: Kara Hamilton, M.S., Nat Pernick, M.D. (see Authors page)

Revised: 29 October 2015, last major update July 2013

Copyright: (c)2003-2015, PathologyOutlines.com, Inc.

PubMed Search: BG7

Table of Contents

Definition / general | Uses by pathologists | Positive staining - normal | Positive staining - disease | Negative staining

Cite this page: BG7. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stainsBG7.html. Accessed July 12th, 2017.

Definition / general

Also called BG-7, anti-Lex, Lewis X antibody
Physiology: recognizes the type 2 chain of the Lewis X blood group antigen

Uses by pathologists

Possibly for screening high risk population for bladder carcinoma (J Urol 2002;168:470)

Positive staining - normal

Granulocytes
Some endothelial cells or erythrocytes

Positive staining - disease

Bladder carcinoma
Reed-Sternberg cells (Cancer 1991;67:1338)
Granulocytic sarcoma
Rare epithelioid histiocytes

Negative staining

Interdigitating reticulum cell sarcoma
Langerhans cell histiocytoma
Malignant histiocytosis
Monoblastic leukemia
Reticulohistiocytoma
Most reactive lymph node conditions