Author: Nat Pernick, M.D.

Revised: 21 March 2018, last major update September 2013

Copyright: (c) 2003-2018,, Inc.

PubMed Search: ACSM1, Acyl-CoA synthetase medium chain family member 1

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Cite this page: Pernick, N. ACSM1. website. Accessed January 22nd, 2019.
Definition / general
  • First discovered in 2001, also called MACS1 (J Biol Chem 2001;276:35961), acyl-CoA synthetase medium-chain family member 1
  • Encodes enzyme catalyzing activation of medium chain length fatty acids (OMIM #614357)
  • Present on chromosome 16p12-13
Clinical features
Uses by pathologists
  • Marker of apocrine breast lesions (benign and malignant)
Microscopic (histologic) images

Images hosted on other servers:

Various normal tissues

Benign breast apocrine lesions

Invasive breast apocrine carcinoma

Kidney tubules (second image in slideshow)

Positive staining - normal
Positive staining - disease