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Table of Contents
Definition / general | Clinical features | Uses by pathologists | Microscopic (histologic) images | Positive staining - normal | Positive staining - diseaseCite this page: ACSM1. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stainsacsm1.html. Accessed July 12th, 2017.
Definition / general
- First discovered in 2001, also called MACS1 (J Biol Chem 2001;276:35961), acyl-CoA synthetase medium-chain family member 1
- Encodes enzyme catalyzing activation of medium chain length fatty acids (OMIM #614357)
- Present on chromosome 16p12-13
Clinical features
- Breast apocrine marker (Mol Cell Proteomics 2008;7:1795)
- Schizophrenia susceptibility gene (J Psychiatr Res 2010;44:748)
- Atlas of Genetics and Cytogenetics
- GeneCards
Uses by pathologists
- Marker of apocrine breast lesions (benign and malignant)
Microscopic (histologic) images
Images hosted on other servers:
Various normal tissues
Benign breast apocrine lesions
Invasive breast apocrine carcinoma
Kidney tubules
Positive staining - normal
- Monocytes (IUBMB Life 2006;58:435)
- Esophagus
Positive staining - disease
- Breast - benign and malignant apocrine lesions (Mol Oncol 2009;3:220)
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