Stains
Cytokeratin AE1


Topic Completed: 1 October 2013

Revised: 5 March 2019

Copyright: 2003-2015, PathologyOutlines.com, Inc.

PubMed Search: AE1[title]

Nat Pernick, M.D.
Page views in 2018: 466
Page views in 2019 to date: 457
Cite this page: Pernick N. Cytokeratin AE1. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stainsae1.html. Accessed December 12th, 2019.
Definition / general
  • Usually used in a cytokeratin cocktail with AE3 (see AE1/AE3)
  • Detects high molecular weight CK10, CK14, CK15 and CK16 and low molecular weight CK19; these are acidic (type I) cytokeratins
Uses by pathologists
Positive staining - normal
Positive staining - disease
Negative staining
Microscopic (histologic) images

Images hosted on other servers:

Liver-bile ducts in severe acute
rejection with dense lymphoid
infiltrate: H&E (top), AE1 (bottom)


Liver-bile ducts in chronic rejection with dense lymphoid infiltrate: H&E (top), AE1 (bottom)

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