Stains
Cytokeratin AE1

Author: Nat Pernick, M.D. (see Authors page)

Revised: 11 December 2015, last major update October 2013

Copyright: (c) 2003-2015, PathologyOutlines.com, Inc.

PubMed Search: AE1[title]
Definition / General
  • Usually used in a cytokeratin cocktail with AE3 (see AE1/AE3)
  • Detects high molecular weight CK10, CK14, CK15 and CK16 and low molecular weight CK19; these are acidic (type I) cytokeratins
Uses by Pathologists
Positive Staining - Normal
Positive Staining - Disease
Negative Staining
Micro Images

Images hosted on other servers:

Liver-bile ducts in severe acute
rejection with dense lymphoid
infiltrate: H&E (top), AE1 (bottom)


Liver-bile ducts in chronic rejection with dense lymphoid infiltrate: H&E (top), AE1 (bottom)