Stains
AMACR


Topic Completed: 1 September 2013

Revised: 2 May 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed Search: AMACR[title]

Gina Johnson, M.D.
Page views in 2018: 15,768
Page views in 2019 to date: 13,603
Cite this page: Johnson G. AMACR. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stainsamacr.html. Accessed September 22nd, 2019.
Definition / general
  • Alpha Methyl Acyl Coenzyme A Racemase; also called P504S
  • Identified from prostate adenocarcinoma by cDNA library subtraction, coupled with high throughput microarray screening of human prostatic tissue
  • A mitochondrial and peroxisomal enzyme involved in beta-oxidation of dietary branched-chain fatty acids and fatty acid derivatives (including bile acid intermediates)
  • AMACR deficiency is rare cause of cerebellar ataxia (Neurology 2011;76:1768)
Uses by pathologists
Microscopic (histologic) images

Images hosted on other servers:

Colonic adenoma

Quality control for AMACR staining


Prostate:

High grade PIN

Adenocarcinoma

Positive stains
Negative stains
Back to top