API2-MALT1

Stains
API2-MALT1

Author: Nat Pernick, M.D. (see Authors page)

Revised: 25 September 2015, last major update June 2005

Copyright: (c) 2003-2015, PathologyOutlines.com, Inc.

PubMed Search: API2-MALT1[title]

Table of Contents

Definition / general | Additional references

Cite this page: API2-MALT1. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stainsapi2malt1.html. Accessed July 12th, 2017.

Definition / general

Fusion protein associated with MALT lymphoma (50%); rarely with diffuse large B cell lymphoma
Due to t(11;18)(q21;q21) - API2 and MALT1
May lead to increased inhibition of apoptosis, helping MALT lymphoma cells to survive

Additional references

Mod Pathol 2003;16:1232
Hum Pathol 2003;34:1212