Apolipoprotein D (apoD)
Reviewer: Nat Pernick, M.D. (see Reviewers page)
Revised: 18 October 2013, last major update June 2005
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
PubMed Search: Apolipoprotein+D[title]
- Member of lipocalin superfamily of proteins involved in transport of cholesterol, steroid hormones and other small hydrophobic molecules
- Correlates with cell cycle inhibition in various situations including cellular senescence
- High levels in fibrocystic breast disease and HDL, but produced by almost all tissues in body
- Expression upregulated in nonneoplastic regenerating peripheral nerve compared to normal, then downregulated during transformation to MPNST (Hum Pathol 2005;36:987)
End of Stains > Apolipoprotein D (apoD)
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