Apolipoprotein D (apoD)

Stains
Apolipoprotein D (apoD)

Author: Nat Pernick, M.D. (see Authors page)

Revised: 25 September 2015, last major update June 2005

Copyright: (c) 2003-2015, PathologyOutlines.com, Inc.

PubMed Search: Apolipoprotein D[title]

Table of Contents

Definition / general

Cite this page: Apolipoprotein D (apoD). PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stainsapod.html. Accessed July 12th, 2017.

Definition / general

Member of lipocalin superfamily of proteins involved in transport of cholesterol, steroid hormones and other small hydrophobic molecules
Correlates with cell cycle inhibition in various situations including cellular senescence
High levels in fibrocystic breast disease and HDL, but produced by almost all tissues in body
Expression upregulated in nonneoplastic regenerating peripheral nerve compared to normal, then downregulated during transformation to MPNST (Hum Pathol 2005;36:987)