Table of ContentsDefinition / general
Cite this page: Pernick N. Apolipoprotein D (apoD). PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stainsapod.html. Accessed May 21st, 2019.
Definition / general
- Member of lipocalin superfamily of proteins involved in transport of cholesterol, steroid hormones and other small hydrophobic molecules
- Correlates with cell cycle inhibition in various situations including cellular senescence
- High levels in fibrocystic breast disease and HDL, but produced by almost all tissues in body
- Expression upregulated in nonneoplastic regenerating peripheral nerve compared to normal, then downregulated during transformation to MPNST (Hum Pathol 2005;36:987)