Apolipoprotein D (apoD)

Author: Nat Pernick, M.D. (see Authors page)

Revised: 25 September 2015, last major update June 2005

Copyright: (c) 2003-2015,, Inc.

PubMed Search: Apolipoprotein D[title]
Table of Contents
  • Member of lipocalin superfamily of proteins involved in transport of cholesterol, steroid hormones and other small hydrophobic molecules
  • Correlates with cell cycle inhibition in various situations including cellular senescence
  • High levels in fibrocystic breast disease and HDL, but produced by almost all tissues in body
  • Expression upregulated in nonneoplastic regenerating peripheral nerve compared to normal, then downregulated during transformation to MPNST (Hum Pathol 2005;36:987)