Reviewer: Nat Pernick, M.D. (see Reviewers page)
Revised: 16 October 2013, last major update June 2005
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
PubMed Search: Cadherins[title]
- See also E-cadherin, N-cadherin
- Molecules that establish links between adjacent cells by forming zipper like structures at adherens junctions
- Linked to cytoskeleton via catenins (cadherin to beta catenin, beta catenin to alpha catenin, alpha catenin to actin) to stabilize adherens junction
- Homophilic interactions (like-like) causes clustering of embryonic cells with others from same tissue
- Loss of cadherins may be first step in giving cells invasive properties
End of Stains > Cadherins
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