Topic Completed: 1 October 2013

Revised: 20 September 2019

Copyright: 2003-2019,, Inc.

PubMed Search: calponin[title]

Nat Pernick, M.D.
Page views in 2018: 4,703
Page views in 2019 to date: 4,520
Cite this page: Pernick N. Calponin. website. Accessed October 21st, 2019.
Definition / general
  • Actin filament associated regulatory protein
  • h1 (basic) isoform is smooth muscle specific, but a late stage smooth muscle marker; described below
  • h2 isoform is found in smooth muscle and non muscle cells; not described below
Uses by pathologists
Microscopic (histologic) images

Case of the Week #62

Sclerosing lobular hyperplasia

Images hosted on other servers:


Adenomyoepithelioma (fig I)


MFH of bone (fig B, F)

Pleomorphic adenoma of nasal cavity (fig 4B)

Positive staining - normal
Positive staining - disease
Negative staining
  • Adenoid cystic carcinoma
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