Stains & molecular markers

Topic Completed: 1 October 2013

Minor changes: 2 September 2020

Copyright: 2003-2020,, Inc.

PubMed Search: calponin[title]

Nat Pernick, M.D.
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Cite this page: Pernick N. Calponin. website. Accessed September 29th, 2020.
Definition / general
  • Actin filament associated regulatory protein
  • h1 (basic) isoform is smooth muscle specific, but a late stage smooth muscle marker; described below
  • h2 isoform is found in smooth muscle and non muscle cells; not described below
Uses by pathologists
Microscopic (histologic) images

Case #62

Sclerosing lobular hyperplasia

Images hosted on other servers:


Adenomyoepithelioma (fig I)


MFH of bone (fig B, F)

Positive staining - normal
Positive staining - disease
Negative staining
  • Adenoid cystic carcinoma
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Image 01 Image 02