CCR2 (CD192)

Author: Nat Pernick, M.D. (see Authors page)

Revised: 18 November 2015, last major update July 2012

Copyright: (c) 2003-2015,, Inc.

PubMed Search: CCR2[title]
Cite this page: CCR2. website. Accessed October 22nd, 2018.
Definition / general
  • Receptor for MCP1, MCP3, MCP4 chemokines; alternative coreceptor with CD4 for HIV1
  • Abbreviation for chemokine C-C motif ligand 2 (CCL2)-chemokine C-C motif receptor 2
  • Also known as CD192, but most publications use CCR2
Clinical features
Uses by pathologists
  • No specific uses by pathologists
Microscopic (histologic) images

Human glomeruli

Lamina propria lymphocytes in small bowel Crohn’s disease and control ileum

Positive staining - normal
  • Neurons, monocytes
  • Controversial if expressed on microglia, or due to infiltrating monocytes