Stains
CCR2 (CD192)



Topic Completed: 1 July 2012

Revised: 18 December 2018, last major update July 2012

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PubMed Search: CCR2[title]
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Cite this page: Pernick N. CCR2. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stainsccr2.html. Accessed March 20th, 2019.
Definition / general
  • Receptor for MCP1, MCP3, MCP4 chemokines; alternative coreceptor with CD4 for HIV1
Terminology
  • Abbreviation for chemokine C-C motif ligand 2 (CCL2)-chemokine C-C motif receptor 2
  • Also known as CD192, but most publications use CCR2
Clinical features
Uses by pathologists
  • No specific uses by pathologists
Microscopic (histologic) images

Human glomeruli


Lamina propria lymphocytes in small bowel Crohn’s disease and control ileum

Positive staining - normal
  • Neurons, monocytes
  • Controversial if expressed on microglia, or due to infiltrating monocytes
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