Table of ContentsDefinition / general
Cite this page: Pernick N. Chaperones. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stainschaperones.html. Accessed May 21st, 2019.
Definition / general
- Proteins which help other proteins fold correctly by transient binding to interactive surfaces (hydrophobic areas), which otherwise might aggregate
- Name is accurate since it has no actual positive effect but prevents negative effects
- Important after environmental stress which causes proteins to unfold
- As a translated protein grows, it becomes increasingly available to chaperones; the protein is released into the intracellular space only when it is folded enough to prevent aggregation