Chaperones

Stains
Chaperones

Author: Nat Pernick, M.D. (see Authors page)

Revised: 24 November 2015, last major update October 2013

Copyright: (c) 2003-2015, PathologyOutlines.com, Inc.

PubMed Search: chaperones[title]

Table of Contents

Definition / general

Cite this page: Chaperones. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stainschaperones.html. Accessed July 12th, 2017.

Definition / general

Proteins which help other proteins fold correctly by transient binding to interactive surfaces (hydrophobic areas), which otherwise might aggregate
Name is accurate since it has no actual positive effect but prevents negative effects
Important after environmental stress which causes proteins to unfold
As a translated protein grows, it becomes increasingly available to chaperones; the protein is released into the intracellular space only when it is folded enough to prevent aggregation