Reviewer: Nat Pernick, M.D. (see Reviewers page)
Revised: 17 October 2013, last major update June 2005
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
PubMed Search: Chloroacetate esterase[title]
- Also called specific esterase, naphthol AS-D chloroacetate esterase
- Useful for demonstrating myeloid differentiation, although negative in 25% of cases, particularly with immature granulocytic and monocytic neoplasms (Arch Pathol Lab Med 2005;129:32)
- Enzyme cytochemistry-positive: AML-M1, M2, microgranular M3; granulocytic sarcomas, neutrophils
- Enzyme cytochemistry-negative: ALL
End of Stains > Chloroacetate esterase
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