Table of ContentsDefinition / general
Cite this page: Pernick N. Chloroacetate esterase. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stainschloroacetate.html. Accessed November 18th, 2019.
Definition / general
- Also called specific esterase, naphthol AS-D chloroacetate esterase
- Useful for demonstrating myeloid differentiation, although negative in 25% of cases, particularly with immature granulocytic and monocytic neoplasms (Arch Pathol Lab Med 2005;129:32)
- Enzyme cytochemistry-positive: AML-M1, M2, microgranular M3; granulocytic sarcomas, neutrophils
- Enzyme cytochemistry-negative: ALL