Stains
Cytokeratin 13 (CK13, K13)

Author: Nat Pernick, M.D. (see Authors page)

Revised: 10 December 2015, last major update October 2013

Copyright: (c) 2003-2015, PathologyOutlines.com, Inc.

PubMed Search: CK13[title]
Cite this page: Cytokeratin 13 (CK13, K13). PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stainsck13.html. Accessed December 9th, 2016.
Definition / General
Uses by Pathologists
  • No significant clinical use by pathologists
Positive Staining - Normal
  • Suprabasal layers of non-cornified stratified epithelium, including squamous (non-keratinized) epithelia of cervix, esophagus, larynx, oral cavity, tonsils, urothelium, and respiratory-type epithelium
  • May be filled with mucoid material or foamy macrophages
Positive Staining - Disease
  • Brenner tumor
  • Squamous metaplasia
  • Squamous cell carcinoma (10%)
  • Urothelial carcinoma (well differentiated)
Negative Staining
  • Epidermis
Additional References