Stains
Cytokeratin 3 (CK3, K3)

Author: Nat Pernick, M.D. (see Authors page)

Revised: 4 December 2015, last major update October 2013

Copyright: (c) 2003-2015, PathologyOutlines.com, Inc.

PubMed Search: ck3
Cite this page: Cytokeratin 3 (CK3, K3). PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stainsck3.html. Accessed December 7th, 2016.
Definition / General
  • Molecular weight is 64-65 kDa
  • Associates with CK12
  • Mutations in KRT3 gene may cause Meesmann corneal dystrophy (Cornea 2005;24:928)
Uses by Pathologists
  • No significant clinical use by pathologists
Positive Staining - Normal
  • Corneal epithelium (full thickness), limbus epithelium (suprabasal)
Negative Staining
  • Conjunctival epithelium
Micro Images

Suprabasal staining of limbus epithelium cultured using air-lifting (AL) technique (fig A/B)

Additional References