Cytokeratin 4 (CK4, K4)

Author: Nat Pernick, M.D. (see Authors page)

Revised: 4 December 2015, last major update October 2013

Copyright: (c) 2003-2015,, Inc.

PubMed Search: ck4[title]
Cite this page: Cytokeratin 4 (CK4, K4). website. Accessed December 16th, 2017.
Definition / general
Uses by pathologists
  • No significant clinical use by pathologists
Case reports
Positive staining - normal
  • Suprabasal cells of nonkeratinized stratified squamous epithelium of esophagus and cornea; also anus, larynx, pharynx, tongue (J Biol Chem 1998;273:23912)
Microscopic (histologic) images

Images hosted on

Epidermis before and after treatment with retinoic acid

Additional references