Cytokeratin 6 (CK6, K6)

Author: Nat Pernick, M.D.

Revised: 16 May 2018, last major update October 2013

Copyright: (c) 2003-2018,, Inc.

PubMed Search: Ck6
Cite this page: Pernick, N. Cytokeratin 6 (CK6, K6). website. Accessed October 22nd, 2018.
Definition / general
Uses by pathologists
Positive staining - normal
  • Esophagus, epidermal and epithelial glands, hair and nails, oral mucosa, stomach, tongue (filiform papillae)
Positive staining - disease
  • Psoriasis, other skin disorders (see above)
Microscopic (histologic) images

Images hosted on other servers:

Keratoconus (fig A), normal cornea (fig D)

Mesothelioma-deciduoid (fig 5)

Squamous cell carcinoma-oral (fig a)

Benign epithelial
inclusions of axillary
lymph nodes
fig 1: CK5/6+; 2: p63+