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Cite this page: Congo red. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stainscongored.html. Accessed July 12th, 2017.
Definition / general
- Also called amyloid stain
- Must examine stained tissue with standard and polarized light
- Amyloid under polarized light has apple green birefringence, based on the molecule being in an antiparallel beta-pleated sheet.
- Note: non-amyloid related green birefringence can occur due to excess dye retained by the tissue
Microscopic (histologic) images
Images hosted on other servers:
Medullary carcinoma of thyroid gland-staining lower right
Amyloid in adrenal gland
Primary localized laryngeal amyloidosis (polarized light-fig F)
Amyloid tumor of breast - fig 1: coarse calcifications of right breast; 2: H&E; 3: Congo red staining; 4: Congo red under polarized light
Images hosted on Nature.com:
Cardiac amyloidosis under polarized light
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