Stains
CXCR2

Author: Nat Pernick, M.D.

Revised: 15 May 2018, last major update January 2012

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Cxcr2 stain
Cite this page: Pernick, N. CXCR2. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stainscxcr2.html. Accessed September 25th, 2018.
Definition / general
  • Interleukin 8 receptor beta subunit (IL8RB); binds multiple CXC chemokines including IL-8 (CXCL8)
  • Chemokine receptor, powerful neutrophil chemotactic factor, particularly to sites of inflammation
Terminology
  • Also called CD182; formerly called CD128b
Diagrams / tables

Images hosted on other servers:

Inflammatory infiltration


Interpretation
  • Cytoplasmic staining
Uses by pathologists
  • No significant uses by pathologists
Microscopic (histologic) images

Images hosted on other servers:

Neuroendocrine cells and neuroendocrine neoplasms

Ovarian carcinoma

Positive staining - normal
Positive staining - disease
  • Carcinoid tumor (classic, atypical, metastatic), pituitary adenoma, pheochromocytoma, medullary carcinoma
Negative staining
  • Parathyroid cells
  • Small cell carcinoma of lung/cervix, large cell lung neuroendocrine carcinoma, Merkel cell carcinoma, neuroblastoma, melanoma