Topic Completed: 1 October 2013

Minor changes: 4 March 2019

Copyright: 2003-2015,, Inc.

PubMed Search: cyclins[title]

Nat Pernick, M.D.
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Table of Contents
Definition / general
Cite this page: Pernick N. Cyclins. website. Accessed August 10th, 2020.
Definition / general
  • Regulatory subunits of cyclin dependent kinases (CDKs)
  • Control the passage of proliferating cells through key checkpoints in the cell cycle (G1 to S, G2 to M) through overexpression of positive growth regulators such as cyclin dependent kinases (CDKs) and underexpression of inhibitory growth regulators, such as CDK inhibitors
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