Stains & CD markers
EBER1, EBER2 and LMP


Last author update: 1 June 2005
Last staff update: 29 July 2022

Copyright: 2002-2024, PathologyOutlines.com, Inc.

PubMed Search: EBER1 / EBER2

Nat Pernick, M.D.
Page views in 2023: 10,219
Page views in 2024 to date: 2,374
Cite this page: Pernick N. EBER1 and EBER2. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainseber1.html. Accessed March 19th, 2024.
Epstein Barr Virus
  • Strongly associated with sinonasal (NK) lymphomas
  • Associated with monoclonal B cell lymphoproliferative disorder (high grade) and immunosuppression (methotrexate) for autoimmune disease
  • Expresses LMP1, which prevents apoptosis via bcl2 interaction
  • Expresses EBER1, which transactivates host genes
EBER1 & EBER2
  • EBV encoded RNA
    • Nuclear RNA portions of EBER1 and 2 genes
  • Interpretation: nuclear stain
LMP
  • Latent Membrane Protein of EBV
  • Interpretation: cytoplasmic or membranous staining
Microscopic (histologic) images

Contributed by Andrey Bychkov, M.D., Ph.D.
Missing Image Missing Image Missing Image

EBER ISH, high power

Missing Image

LMP in EBV+ nasopharyngeal carcinoma

Back to top
Image 01 Image 02