Topic Completed: 1 April 2012

Revised: 5 March 2019

Copyright: 2002-2018,, Inc.

PubMed Search: eIF-4F [title]

Nat Pernick, M.D.
Page views in 2019: 19
Page views in 2020 to date: 1
Cite this page: Pernick N. eIF-4F. website. Accessed February 19th, 2020.
Definition / general
  • Eukaryotic initiation factor 4F mediates the initiation of cellular mRNA translation (EMBO J 2008;27:3129)
  • eIF-4F activity is controlled by a repressor binding protein (4E-BP1), which promotes translation when phosphorylated (Arch Pathol Lab Med 2011;135:365)
Uses by pathologists
  • None at this time
Diagrams / tables

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Phosphorylation status

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