Stains
eIF-4F

Author: Nat Pernick, M.D. (see Authors page)

Revised: 17 December 2015, last major update April 2012

Copyright: (c) 2002-2015, PathologyOutlines.com, Inc.

PubMed Search: eIF-4F [title]

Definition / General
  • Eukaryotic initiation factor 4F mediates the initiation of cellular mRNA translation (EMBO J 2008;27:3129)
  • eIF-4F activity is controlled by a repressor binding protein (4E-BP1), which promotes translation when phosphorylated (Arch Pathol Lab Med 2011;135:365)
Uses by Pathologists
  • None at this time
Diagrams / Tables

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Eukaryotic translation initiation

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Phosphorylation status