Stains - ETV6-NTRK3

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Stains

ETV6-NTRK3

Reviewer: Nat Pernick, M.D. (see Reviewers page)
Revised: 24 March 2012, update in progress
Copyright: (c) 2002-2011, PathologyOutlines.com, Inc.

Definition
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● Gene fusion product associated with breast secretory carcinoma (Mod Pathol 2009;22:291, Semin Cancer Biol 2005;15:215), congenital mesoblastic nephroma-cellular subtype, infantile (congenital) fibrosarcoma (Mod Pathol 2000;13:29, Mod Pathol 2001;14:1246)
● Also AML (Blood 1999;93:1355)
● ETV6 on 12p13 is fused to NTRK3 on 15q25 via t(12;15)(p13;q25)

Diagrams
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Schematic

Molecular images
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Ideogram and FISH

Gel for fusion transcript

End of Stains > ETV6-NTRK3

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