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Stains

Factor VIII related antigen


Reviewer: Nat Pernick, M.D. (see Reviewers page)
Revised: 24 July 2012, last major update April 2012-in progress
Copyright: (c) 2002-2012, PathologyOutlines.com, Inc.

Definition
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Interpretation: cytoplasmic stain; endothelium acts as a positive internal control

Uses by pathologists
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● Common endothelial marker

Micro images
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Capillary hemangioma of endometrium (fig 2B)


Cribriform DCIS of breast - fig 2a: factor VIII staining shows only rare vascular proliferation; 2b: low MIB1 staining

Positive staining - normal
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● Endothelial cells, megakaryocytes, platelets and mast cells

Positive staining - disease
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● Vascular tumors

Additional references
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Link

End of Stains > Factor VIII related antigen


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