Stains
Factor VIII related antigen



Topic Completed: 1 July 2012

Revised: 5 March 2019

Copyright: 2003-2015, PathologyOutlines.com, Inc.

PubMed Search: Factor VIII related antigen
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Cite this page: Pernick N. Factor VIII related antigen. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stainsfactorviii.html. Accessed May 21st, 2019.
Definition / general
  • Interpretation: cytoplasmic stain; endothelium acts as a positive internal control
Uses by pathologists
  • Common endothelial marker
Microscopic (histologic) images

Images hosted on other servers:

Capillary hemangioma of endometrium (fig 2B)


Cribriform DCIS of breast - fig 2a: factor VIII staining shows only rare vascular proliferation; 2b: low MIB1 staining

Positive staining - normal
  • Endothelial cells, megakaryocytes, platelets and mast cells
Positive staining - disease
  • Vascular tumors
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