Author: Nat Pernick, M.D. (see Authors page)

Revised: 17 December 2015, last major update February 2012

Copyright: (c) 2003-2015,, Inc.

PubMed Search: FOXA1
Cite this page: FOXA1. website. Accessed May 21st, 2018.
Definition / general
  • Forkhead box A1 gene; also known as HNF3α (hepatocyte nuclear factor 3α)
  • DNA binding protein that acts as transcriptional activator for liver specific transcripts such as albumin and transthyretin; also interacts with chromatin
  • Marker of luminal A type breast cancer
Uses by pathologists
Microscopic (histologic) images

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FOXA1 and GATA3 in breast cancer cases

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FOXA1 and GATA3 in breast cancer cases