Hales colloidal iron

Topic Completed: 1 June 2005

Revised: 5 March 2019

Copyright: 2003-2015,, Inc.

PubMed Search: colloidal iron[title]

Nat Pernick, M.D.
Page views in 2018: 2,289
Page views in 2019 to date: 1,830
Cite this page: Pernick N. Hales colloidal iron. website. Accessed September 16th, 2019.
Definition / general
  • Kidney tumors: stain must have pH between 1.5 and 2.0
  • Clear cell and papillary renal carcinoma have focal, coarse, droplike staining
  • Note: hemosiderin in any tumors will also stain positive
Uses by pathologists
  • Helpful in distinguishing chromophobe renal cell carcinoma (intensely positive in large percentage of cells with reticular staining) from oncocytoma (usually negative; if positive - fewer cells with less intensity and dustlike staining)
Back to top