Author: Nat Pernick, M.D. (see Authors page)

Revised: 14 February 2017, last major update June 2005

Copyright: (c) 2003-2017,, Inc.

PubMed Search: HBME

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Cite this page: HBME. website. Accessed January 22nd, 2019.
Definition / general
  • Also called HBME-1
  • Marker of mesothelial cells, named after laboratory of Dr. Hector Battifora and MEsothelioma
  • Also positive in various thyroid carcinomas
Microscopic (histologic) images

Images hosted on PathOut server:

Contributed by Andrey Bychkov, M.D., Ph.D.:

Tumor interface

Striking membranous staining

Strong membranous HBME-1 immunoreactivity

Strong HBME-1 immunoreactivity with apical membrane accentuation