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Stains

HPC2


Reviewer: Nat Pernick, M.D. (see Reviewers page)
Revised: 27 April 2013, last major update April 2013
Copyright: (c) 2002-2012, PathologyOutlines.com, Inc.

Definition
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● Human pancreatic cancer fusion #2
● Note: also denotes a histone chaperone gene (Biochem Biophys Res Commun 2012;418:414, Mol Biosyst 2009;5:269)
● Also denotes PcG protein (Polycomb group) hPc2 (BMB Rep 2009;42:154, Int J Biochem Cell Biol 2008;40:2462)

Micro images
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Pancreatic ductal adenocarcinoma

Positive staining - disease
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● Ampullary carcinoma (82%), cholangiocarcinoma (32%), pancreatic adenocarcinoma (80%, well/moderate > poorly differentiated, Hum Pathol 2012;43:1583, Cancer Cytopathol 2013;121:37)
● Also pancreatic IPMN

Negative staining
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● Colon and gallbladder carcinoma

End of Stains > HPC2


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