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General
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Pathophysiology
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Role in TCA cycle

Reactions catalyzed by wild-type and mutant IDH1 and IDH2

Uses by pathologists
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Micro images
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Kidney: normal


Astrocytoma

Gliosarcoma

Oligoastrocytoma, anaplastic


Glioblastoma:

Various images


With PNET-like foci

Granular cell glioblastoma

Giant cell glioblastoma

With oligodendroglial component


Positive staining / mutations - disease
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Negative staining
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End of Stains > IDH1





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