Stains
IL8



Topic Completed: 1 August 2014

Revised: 6 March 2019

Copyright: 2003-2014, PathologyOutlines.com, Inc.

PubMed Search: IL-8[title], CXCL8[title]
Page views in 2018: 27
Page views in 2019 to date: 14
Cite this page: Pernick N. IL8. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stainsil8.html. Accessed March 24th, 2019.
Definition / general
  • Proinflammatory and pro-angiogenic chemokine
  • Produced by endothelial cells, epithelial cells, goblet cells (Clin Exp Allergy 2014;44:540), macrophages, mesothelial cells, smooth muscle cells in airways (Wikipedia) and various tumor cells (see below)
  • Also known as CXCL8
Pathophysiology
Clinical features
Uses by pathologists
  • No definite uses at this time
Microscopic (histologic) images

Cervical cancer

Positive staining - normal
  • Endothelial cells, epithelial cells, goblet cells, macrophages, mesothelial cells, smooth muscle cells in airways
Positive staining - malignant
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