Author: Nat Pernick, M.D. (see Authors page)

Revised: 24 November 2015, last major update June 2005

Copyright: (c) 2002-2015,, Inc.

PubMed Search: Interleukins [title]

Table of Contents
Definition / General | See also
Definition / General
  • Soluble factors which stimulate growth-related activities of leukocytes as well as other cell types
  • Enhance cell proliferation and differentiation, DNA synthesis, secretion of other biologically active molecules and responses to immune and inflammatory stimuli
  • Promote survival of resting T cells which do not proliferate in response to IL-2, 4 or 7
  • IL 2, 4 and 7 receptors share a common gamma chain
See also
    Interleukin 2 (IL-2)
    • General:
      • Potent inducer of CTLA-4
      • Potent survival factor for lymphocytes

    Interleukin 6 (IL-6)
    • General:
      • Induces thrombocytosis by stimulating thrombopoietin
      • Produced continuously by all mesothelioma cell lines
    • Micro images:

      Missing Image

      Diffusely stained