Author: Nat Pernick, M.D. (see Authors page)

Revised: 3 August 2018, last major update June 2005

Copyright: (c) 2002-2018,, Inc.

PubMed Search: Interleukins [title]

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Table of Contents
Definition / general | See also
Cite this page: Pernick, N. Interleukins. website. Accessed January 18th, 2019.
Definition / general
  • Soluble factors which stimulate growth-related activities of leukocytes as well as other cell types
  • Enhance cell proliferation and differentiation, DNA synthesis, secretion of other biologically active molecules and responses to immune and inflammatory stimuli
  • Promote survival of resting T cells which do not proliferate in response to IL-2, 4 or 7
  • IL 2, 4 and 7 receptors share a common gamma chain
See also
    Interleukin 2 (IL-2)
    • General:
      • Potent inducer of CTLA-4
      • Potent survival factor for lymphocytes

    Interleukin 6 (IL-6)
    • General:
      • Induces thrombocytosis by stimulating thrombopoietin
      • Produced continuously by all mesothelioma cell lines