Stains & molecular markers
ISL1



Topic Completed: 1 November 2013

Minor changes: 3 September 2020

Copyright: 2015-2020, PathologyOutlines.com, Inc.

PubMed Search: ISL1[title]

Nat Pernick, M.D.
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Cite this page: Pernick N. ISL1. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/stainsisl1.html. Accessed October 24th, 2020.
Definition / general
  • Insulin gene enhancer-binding protein islet-1 (ISL1); also called ISLET1, LIM homeodomain gene Islet-1 (GeneCards)
Microscopic (histologic) images

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Heart between 26 and 38 days of gestation

Positive staining - normal
Positive staining - disease
  • Pancreatic (well differentiated) and other neuroendocrine tumors
Negative staining
  • Poorly differentiated pancreatic endocrine tumors
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