Stains & molecular markers

Topic Completed: 1 June 2005

Minor changes: 3 September 2020

Copyright: 2003-2020,, Inc.

PubMed Search: Lambda[title]

Nat Pernick, M.D.
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Cite this page: Pernick N. Lambda. website. Accessed September 28th, 2020.
Definition / general
  • Type of immunoglobulin light chain
  • Kappa/lambda ratio is usually 2:1
  • Restricted expression of either kappa or lambda suggests monoclonality and a neoplastic process
Microscopic (histologic) images

AFIP images

Hodgkin lymphoma

Contributed by Leica Microsystems, Biosystems division

Myeloma of bone marrow with ISH staining for
kappa (left) and lambda (right) light chains using
Kappa Probe (PB0645), Lambda Probe (PB0669)
and Bond Polymer Refine Detection

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Image 01 Image 02