Leder stain

Author: Nat Pernick, M.D. (see Authors page)

Revised: 3 November 2015, last major update June 2005

Copyright: (c) 2003-2015,, Inc.

PubMed Search: Leder[title] or chloroacetate esterase[title]

Definition / General
  • Type of enzyme histochemistry
  • Also called chloroacetate esterase
  • Chloroacetate esterase resists effects of formalin fixation and paraffin embedding
Uses by Pathologists
  • Identify mast cell disorders, myeloid disorders
Positive Staining - Normal
  • Mast cells, myeloid cells