Lipochrome (lipofuscin) pigments

Author: Nat Pernick, M.D. (see Authors page)

Revised: 6 November 2015, last major update June 2005

Copyright: (c) 2003-2015,, Inc.

PubMed Search: Lipofuscin[title]

Definition / General
  • Breakdown products within cells from oxidation of lipids and lipoproteins
  • Also called “wear and tear” pigments in heart, liver, CNS, adrenal cortex (zona reticularis), testis interstitium and seminal vesicle
  • Stains with Sudan black B, long Ziehl-Neelson acid fast, Schmorl methods
  • Lipochrome may have strong orange autofluorescence in formalin-fixed, unstained paraffin sections
Micro Images